Gene Expression Literature Summary

• Symbol: Hmgn2
• Name: high mobility group nucleosomal binding domain 2
• ID: MGI:96136

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E2	E9.5	E10.5	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)				2	1			1	1	1	1	1		1	1	1		1			4
In situ RNA (section)					3	1	1		3	1	3		4	1			2	1	2		3
Immunohistochemistry (whole mount)	1	1																			1
In situ RNA (whole mount)			1	1	1								1
In situ reporter (knock in)				1			1				1				1				1		2
Northern blot					1					1	2	1					2				2
Western blot											1									1
RT-PCR	1	1		1					2		2				3				2		4
cDNA clones				1					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hmgn2  high mobility group nucleosomal binding domain 2   (Synonyms: Hmg17, HMG-17)
Results	Reference
1	J:28401 Bettenhausen B, Gossler A, Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos. Genomics. 1995 Aug 10;28(3):436-41
5*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
11	J:327958 Eliason S, Su D, Pinho F, Sun Z, Zhang Z, Li X, Sweat M, Venugopalan SR, He B, Bustin M, Amendt BA, HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. J Biol Chem. 2022 Jul 21;298(9):102295
3*	J:92176 Ficker M, Powles N, Warr N, Pirvola U, Maconochie M, Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule. Dev Biol. 2004 Apr 1;268(1):7-23
1*	J:148798 Furusawa T, Ko JH, Birger Y, Bustin M, Expression of nucleosomal protein HMGN1 in the cycling mouse hair follicle. Gene Expr Patterns. 2009 Jun;9(5):289-95
14*	J:284573 Gao XL, Tian WJ, Liu B, Wu J, Xie W, Shen Q, High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis. J Biol Chem. 2020 Jan 10;295(2):468-480
2*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:210222 Hupe M, Li MX, Gertow Gillner K, Adams RH, Stenman JM, Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Nucleic Acids Res. 2014 Jan;42(2):e14
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
7	J:70582 Lehtonen S, Lehtonen E, HMG-17 is an early marker of inductive interactions in the developing mouse kidney. Differentiation. 2001 Jun;67(4-5):154-63
4*	J:49691 Lehtonen S, Olkkonen VM, Stapleton M, Zerial M, Lehtonen E, HMG-17, a chromosomal non-histone protein, shows developmental regulation during organogenesis. Int J Dev Biol. 1998 Sep;42(6):775-82
7	J:203117 Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA, A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. Hum Mol Genet. 2014 Jan 1;23(1):194-208
1	J:284156 Lo Giudice Q, Leleu M, La Manno G, Fabre PJ, Single-cell transcriptional logic of cell-fate specification and axon guidance in early-born retinal neurons. Development. 2019 Sep 9;146(17):dev178103
5*	J:137620 Lucey MM, Wang Y, Bustin M, Duncan MK, Differential expression of the HMGN family of chromatin proteins during ocular development. Gene Expr Patterns. 2008 Jul;8(6):433-7
6	J:66810 Mohamed OA, Bustin M, Clarke HJ, High-mobility group proteins 14 and 17 maintain the timing of early embryonic development in the mouse. Dev Biol. 2001 Jan 1;229(1):237-49
1	J:291493 Najas S, Pijuan I, Esteve-Codina A, Usieto S, Martinez JD, Zwijsen A, Arbones ML, Marti E, Le Dreau G, A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex. Development. 2020 Jul 13;147(13):dev187005
4	J:10494 Pash J, Popescu N, Matocha M, Rapoport S, Bustin M, Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16. Proc Natl Acad Sci U S A. 1990 May;87(10):3836-40
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1*	J:310323 Vied CM, Freudenberg F, Wang Y, Raposo AA, Feng D, Nowakowski RS, A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development. Front Neurosci. 2014;8:257
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48