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Symbol Name ID |
Siglec1
sialic acid binding Ig-like lectin 1, sialoadhesin MGI:99668 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | impaired macrophage phagocytosis |
abnormal B cell number |
decreased follicular B cell number |
increased marginal zone B cell number |
abnormal T cell subpopulation ratio |
increased CD8-positive, alpha-beta T cell number |
decreased IgM level |
decreased circulating interleukin-6 level |
decreased circulating tumor necrosis factor level |
decreased interleukin-10 secretion |
decreased interleukin-12 secretion |
decreased interleukin-6 secretion |
decreased tumor necrosis factor secretion |
decreased susceptibility to bacterial infection |
increased susceptibility to bacterial infection |
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| Availability | Mouse Genotype | |||||||||||||||
| Siglec1tm1Croc/Siglec1tm1Croc | ||||||||||||||||
| Siglec1tm2.1Croc/Siglec1tm2.1Croc | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/08/2026 MGI 6.24 |
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