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Symbol
Name
ID
Aldh2
aldehyde dehydrogenase 2, mitochondrial
MGI:99600
Phenotype annotations related to liver/biliary system
Darker colors indicate more annotations
Human Phenotypes
Hepatic steatosis
Hepatosplenomegaly
Micronodular cirrhosis
Subacute progressive viral hepatitis
Extrahepatic cholestasis
Jaundice
Neoplasm of the liver
Hepatocellular carcinoma
Disease(s) Associated with ALDH2
hepatocellular carcinoma
metabolic dysfunction-associated steatotic liver disease
pancreatic cancer

Mouse Phenotypes
increased hepatocyte apoptosis
abnormal hepatocyte respiration
decreased liver enzyme/coenzyme activity
Availability Mouse Genotype
Aldh2tm1.1Mak/Aldh2tm1.1Mak
Aldh2tm1Kaw/Aldh2tm1Kaw
Aldh2tm1.1Mak/Aldh2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory