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Symbol
Name
ID
Mc4r
melanocortin 4 receptor
MGI:99457
Phenotype annotations related to growth/size/body
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased waist to hip ratio
Obesity
Disease(s) Associated with MC4R
obesity

Mouse Phenotypes
growth/size/body region phenotype
increased body mass index
decreased lean body mass
increased lean body mass
decreased body weight
increased body weight
obese
increased body length
increased susceptibility to weight gain
increased susceptibility to diet-induced obesity
increased body size
increased liver weight
Availability Mouse Genotype
Mc4rGlu3/Mc4rGlu3
Mc4rI194F/Mc4rI194F
Mc4rm1Btlr/Mc4rm1Btlr
Mc4rm2Btlr/Mc4rm2Btlr
Mc4rm3Btlr/Mc4rm3Btlr
Mc4rM4Btlr/Mc4rM4Btlr
Mc4rM5Btlr/Mc4rM5Btlr
Mc4rM6Btlr/Mc4rM6Btlr
Mc4rm7Btlr/Mc4rm7Btlr
Mc4rtm1.1Fbz/Mc4rtm1.1Fbz
Mc4rtm1Dhu/Mc4rtm1Dhu
Mc4rtm1Lowl/Mc4rtm1Lowl
Mc4rtm1Matsu/Mc4rtm1Matsu
Mc4rtm2.1Lowl/Mc4rtm2.1Lowl
Mc4rY302C/Mc4rY302C
Mc4rGlu3/Mc4r+
Mc4rI194F/Mc4r+
Mc4rm3Btlr/Mc4r+
Mc4rM4Btlr/Mc4r+
Mc4rMhdahwe13/Mc4r+
Mc4rPkcp/Mc4r+
Mc4rtm1.1Fbz/Mc4r+
Mc4rtm1Lowl/Mc4r+
Mc4rY302C/Mc4r+
Mc4rtm1Lowl/Mc4rtm1Lowl
Tg(Sim1-cre)1Lowl/0  (conditional)
*
Mc4rtm1Lowl/Mc4rtm1Lowl
Tg(Sim1-cre)2Lowl/0  (conditional)
Mc4rtm1Lowl/Mc4rtm1Lowl
Slc17a6tm2(cre)Lowl/Slc17a6+  (conditional)
*
Mc4rtm1Lowl/Mc4rtm1Lowl
Slc32a1tm2(cre)Lowl/Slc32a1+  (conditional)
Mc4rtm1Lowl/Mc4rtm1Lowl
Oxttm1.1(cre)Dolsn/Oxt+  (conditional)
Crhtm1.1(cre)Dolsn/Crh+
Mc4rtm1Lowl/Mc4rtm1Lowl  (conditional)
Mc4rtm1Lowl/Mc4rtm1Lowl
Pdyntm1.1(cre)Mjkr/Pdyn+  (conditional)
Crhtm1.1(cre)Dolsn/Crh+
Mc4rtm1Lowl/Mc4rtm1Lowl
Oxttm1.1(cre)Dolsn/Oxt+  (conditional)
Mc4rtm2Lowl/Mc4rtm2Lowl
Tg(Sim1-cre)1Lowl/0  (conditional)
Mc4rtm2Lowl/Mc4rtm2Lowl
Slc17a6tm2(cre)Lowl/Slc17a6+  (conditional)
Mc4rtm2Lowl/Mc4rtm2Lowl  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory