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Symbol
Name
ID

Trp53
transformation related protein 53
MGI:98834

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes	Central retinal vessel vascular tortuosity	Neoplasia of the nasopharynx
Disease(s) Associated with TP53	Central retinal vessel vascular tortuosity	Neoplasia of the nasopharynx
Leber hereditary optic neuropathy
nasopharynx carcinoma

Mouse Phenotypes		abnormal craniofacial morphology	short mandible	square face	cleft upper lip	oral leukoplakia	cleft palate	abnormal tongue morphology	protruding tongue	abnormal outer ear morphology	increased ear pigmentation
Availability	Mouse Genotype	abnormal craniofacial morphology	short mandible	square face	cleft upper lip	oral leukoplakia	cleft palate	abnormal tongue morphology	protruding tongue	abnormal outer ear morphology	increased ear pigmentation
	Trp53^tm1.1Tldo/Trp53^tm1.1Tldo
	Trp53^tm1Att/Trp53⁺ Tg(KRT5-cre)5132Jlj/0 (conditional)
	Tg(CMV-cre)1Cgn/0 Trp53^tm4Att/Trp53⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23