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Symbol
Name
ID
Sox11
SRY (sex determining region Y)-box 11
MGI:98359
Phenotype annotations related to vision/eye
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Ptosis
Disease(s) Associated with SOX11
Coffin-Siris syndrome 9

Mouse Phenotypes
vision/eye phenotype
increased retina apoptosis
decreased amacrine cell number
decreased retina ganglion cell number
abnormal retina bipolar cell morphology
optic nerve hypoplasia
abnormal eye development
microphthalmia
abnormal eyelid morphology
eyelids open at birth
abnormal retina morphology
thin retina ganglion layer
thin retina inner nuclear layer
Availability Mouse Genotype
Sox11tm1Weg/Sox11tm1Weg
Sox11tm2.2Weg/Sox11tm2.2Weg
Sox11tm1.1Gan/Sox11tm1.1Gan
Tg(Six3-cre)69Frty/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory