About Help FAQ

Symbol
Name
ID

Sos1
SOS Ras/Rac guanine nucleotide exchange factor 1
MGI:98354

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Low posterior hairline	Cystic hygroma	Thickened nuchal skin fold	Short neck	Webbed neck	Hepatomegaly	Aplasia/Hypoplasia of the abdominal wall musculature	Delayed menarche	Short stature	Large for gestational age	Postnatal growth retardation
Disease(s) Associated with SOS1	Low posterior hairline	Cystic hygroma	Thickened nuchal skin fold	Short neck	Webbed neck	Hepatomegaly	Aplasia/Hypoplasia of the abdominal wall musculature	Delayed menarche	Short stature	Large for gestational age	Postnatal growth retardation
Noonan syndrome
Noonan syndrome 4

Mouse Phenotypes		heart left ventricle hypertrophy	heart right ventricle hypertrophy	enlarged heart	cleft palate	decreased embryo size	decreased body weight	decreased body length	decreased body size	enlarged spleen
Availability	Mouse Genotype	heart left ventricle hypertrophy	heart right ventricle hypertrophy	enlarged heart	cleft palate	decreased embryo size	decreased body weight	decreased body length	decreased body size	enlarged spleen
	Sos1^tm1.2Rak/Sos1^tm1.2Rak
	Sos1^tm1Dlb/Sos1^tm1Dlb
	Sos1^tm1.2Rak/Sos1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23