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Symbol
Name
ID
Sod2
superoxide dismutase 2, mitochondrial
MGI:98352
Phenotype annotations related to growth/size/body
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Thickened nuchal skin fold
Splenomegaly
Hepatosplenomegaly
Peritoneal abscess
Tall stature
Increased waist to hip ratio
Weight loss
Disease(s) Associated with SOD2
multiple myeloma
pancreatic cancer
pseudoxanthoma elasticum
systemic lupus erythematosus
type 2 diabetes mellitus

Mouse Phenotypes
increased heart weight
enlarged heart
cardiac hypertrophy
growth/size/body region phenotype
decreased body weight
decreased body length
decreased body size
postnatal growth retardation
decreased fetal size
increased liver weight
Availability Mouse Genotype
Sod2tm1.1Kskk/Sod2tm1.1Kskk
Sod2tm1Cje/Sod2tm1Cje !
Sod2tm1Leb/Sod2tm1Leb
Sod2tm1Shs/Sod2tm1Shs
Tg(TNNI2-icre)1Vrmn/0  (conditional)
*
Sod2tm1Shs/Sod2tm1Shs
Tg(Cdh16-cre)91Igr/0  (conditional)
Sod2tm1Shs/Sod2tm1Shs
Tg(Ckmm-cre)5Khn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory