Symbol
Name
ID

Sod1
superoxide dismutase 1, soluble
MGI:98351

Phenotype annotations related to hearing/vestibular/ear

Darker colors indicate more annotations

Human Phenotypes	Conductive hearing impairment	Microtia	Round ear	Sensorineural hearing impairment
Disease(s) Associated with SOD1	Conductive hearing impairment	Microtia	Round ear	Sensorineural hearing impairment
Down syndrome
retinitis pigmentosa

Mouse Phenotypes

cochlear inner hair cell degeneration

cochlear outer hair cell degeneration

cochlear hair cell degeneration

pillar cell degeneration

organ of Corti degeneration

thin stria vascularis

abnormal auditory brainstem response waveform shape

increased or absent threshold for auditory brainstem response

increased susceptibility to age-related hearing loss

increased susceptibility to noise-induced hearing loss

deafness

Availability

Mouse Genotype

Sod1^tm1Cep/Sod1^tm1Cep

Sod1^tm1Leb/Sod1^tm1Leb

Sod1^tm1Cep/Sod1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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