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Symbol
Name
ID

Sim1
single-minded family bHLH transcription factor 1
MGI:98306

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased resting energy expenditure
Disease(s) Associated with SIM1	Decreased resting energy expenditure
obesity

Mouse Phenotypes		increased susceptibility to diet-induced obesity	increased glycosylated hemoglobin level	increased circulating glucose level	hyperglycemia	increased circulating insulin level	increased circulating leptin level	abnormal energy homeostasis	abnormal glucose homeostasis	increased urine glucose level	insulin resistance
Availability	Mouse Genotype	increased susceptibility to diet-induced obesity	increased glycosylated hemoglobin level	increased circulating glucose level	hyperglycemia	increased circulating insulin level	increased circulating leptin level	abnormal energy homeostasis	abnormal glucose homeostasis	increased urine glucose level	insulin resistance
	Sim1^Rgsc646/Sim1⁺
	Sim1^tm1.1Az/Sim1⁺
	Sim1^tm1Fan/Sim1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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