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Symbol
Name
ID
Ccl2
C-C motif chemokine ligand 2
MGI:98259
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgE level
Elevated erythrocyte sedimentation rate
Diabetes mellitus
Pleural effusion
Fever
Hematuria
Pyuria
Decreased level of D-mannose in urine
Proteinuria
Pancreatic calcification
Disease(s) Associated with CCL2
Behcet's disease
pancreatitis
systemic lupus erythematosus
temporal arteritis
thrombocytopenia

Mouse Phenotypes
abnormal response to cardiac infarction
decreased susceptibility to neuronal excitotoxicity
increased susceptibility to diet-induced obesity
increased circulating glucose level
decreased circulating insulin level
increased circulating insulin level
increased circulating leptin level
decreased circulating free fatty acids level
increased circulating interferon-gamma level
increased circulating interleukin-10 level
increased circulating tumor necrosis factor level
abnormal glucose homeostasis
abnormal gluconeogenesis
impaired glucose tolerance
improved glucose tolerance
increased insulin sensitivity
decreased adiponectin level
increased adiponectin level
abnormal chemokine level
decreased susceptibility to xenobiotic induced morbidity/mortality
decreased physiological sensitivity to xenobiotic
decreased incidence of tumors by chemical induction
abnormal response to injury
delayed wound healing
Availability Mouse Genotype
Ccl2tm1.1Tyos/Ccl2tm1.1Tyos
Ccl2tm1Rol/Ccl2tm1Rol
Ccl2tm1Tyos/Ccl2tm1Tyos

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory