Symbol
Name
ID

Rxra
retinoid X receptor alpha
MGI:98214

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes	Breast carcinoma	Jaundice
Disease(s) Associated with RXRA	Breast carcinoma	Jaundice
pancreatic cancer

Mouse Phenotypes

increased keratinocyte proliferation

dermal cyst

skin edema

skin inflammation

abnormal hair follicle melanin granule distribution

diluted coat color

abnormal hair growth

alopecia

delayed hair appearance

thin hypodermis

abnormal hair follicle morphology

disorganized outer root sheath cells

abnormal piliary canal morphology

dilated piliary canal

distorted hair follicle pattern

hair follicle degeneration

abnormal hair cycle anagen phase

abnormal hair cycle telogen phase

abnormal skin morphology

thick dermal layer

abnormal epidermis stratum corneum morphology

hyperkeratosis

thick epidermis suprabasal layer

abnormal keratinocyte morphology

pallor

scaly skin

shiny skin

skin lesions

translucent skin

abnormal skin condition

Availability

Mouse Genotype

Rxra^pke/Rxra^pke

Rxra^tm1Ipc/Rxra^tm1Ipc

Rxra^tm1Rev/Rxra^tm1Rev

Rxra^tm4.1Ipc/Rxra^tm4.1Ipc

Rxra^tm2Ipc/Rxra^tm4.1Ipc

Rxra^tm4Ipc/Rxra^tm4Ipc
Tg(KRT14-cre)1Ipc/0 (conditional)

Rxra^tm2Ipc/Rxra^tm4Ipc
Tg(KRT14-cre)1Ipc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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