Symbol Name ID |
Nras
neuroblastoma ras oncogene MGI:97376 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Leukemia |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Juvenile myelomonocytic leukemia |
Lymphoma |
Lymphoproliferative disorder |
Multiple myeloma |
Myelodysplasia |
Adenoma sebaceum |
Hemangioma |
Cavernous hemangioma |
Hereditary nonpolyposis colorectal carcinoma |
Neoplasm of the stomach |
Hepatocellular carcinoma |
Non-medullary thyroid carcinoma |
Papillary thyroid carcinoma |
Uterine leiomyosarcoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Neoplasm of the skin |
Basal cell carcinoma |
Cutaneous melanoma |
Rhabdomyosarcoma |
Neoplasm |
Sarcoma |
Disease(s) Associated with NRAS | ||||||||||||||||||||||||||
acute lymphoblastic leukemia | ||||||||||||||||||||||||||
acute myeloid leukemia | ||||||||||||||||||||||||||
autoimmune lymphoproliferative syndrome type 4 | ||||||||||||||||||||||||||
colorectal cancer | ||||||||||||||||||||||||||
hepatocellular carcinoma | ||||||||||||||||||||||||||
large congenital melanocytic nevus | ||||||||||||||||||||||||||
linear nevus sebaceous syndrome | ||||||||||||||||||||||||||
multiple myeloma | ||||||||||||||||||||||||||
myelodysplastic syndrome | ||||||||||||||||||||||||||
Noonan syndrome 6 | ||||||||||||||||||||||||||
thyroid gland papillary carcinoma |
Mouse Phenotypes | neoplasm |
increased acute lymphoblastic leukemia incidence |
increased melanoma incidence |
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Availability | Mouse Genotype | |||
Nrastm1Tyj/Nrastm1Tyj Tg(Mx1-cre)1Cgn/0 (conditional) |
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Nrastm1Tyj/Nrastm1Tyj Tg(Tyr-cre/ERT2)1Lru/0 (conditional) |
* | |||
Nrastm1Tyj/Nrastm1Tyj Tg(Tyr-cre)1Lru/0 (conditional) |
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Meox2tm1(cre)Sor/? Nrastm1Zhng/Nrastm1Zhng (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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