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Symbol
Name
ID
Notch2
notch 2
MGI:97364
Phenotype annotations related to cellular
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cellular phenotype
absent mesangial cell
abnormal cell cycle
increased embryonic tissue cell apoptosis
increased kidney apoptosis
increased neuron apoptosis
increased apoptosis
focal hepatic necrosis
abnormal osteoclast differentiation
increased B cell proliferation
decreased kidney cell proliferation
Availability Mouse Genotype
Notch2tm1Grid/Notch2tm1Grid
Notch2tm1Yha/Notch2tm1Yha
Notch2tm1.1Ecan/Notch2+
Notch2tm1.1Hhtg/Notch2+
Notch2tm3Grid/Notch2tm3Grid
Tg(Pax3-cre)1Joe/0  (conditional)
*
Notch2tm3Grid/Notch2tm3Grid
Foxg1tm1(cre)Skm/Foxg1+  (conditional)
Gt(ROSA)26Sortm2(CAG-Notch2*)Uzs/Gt(ROSA)26Sor+
Cd19tm1(cre)Cgn/Cd19+  (conditional)
Notch2tm2Grid/Notch2tm3Grid
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Notch2tm3Grid/Notch2tm3.1Grid
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory