Symbol
Name
ID

Nek1
NIMA (never in mitosis gene a)-related expressed kinase 1
MGI:97303

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes

Brachycephaly

Postaxial hand polydactyly

Preaxial hand polydactyly

Postaxial foot polydactyly

Postaxial polysyndactyly of foot

Polysyndactyly of hallux

Toe syndactyly

Brachydactyly

Disproportionate shortening of the tibia

Short foot

Abnormal metaphysis morphology

Mesomelia

Micromelia

Cone-shaped epiphysis

Short long bone

Abnormal pelvic girdle bone morphology

Abnormal clavicle morphology

Lateral clavicle hook

Abnormal rib morphology

Short ribs

Horizontal ribs

Thoracic dysplasia

Abnormal sternum morphology

Pectus carinatum

Short thorax

Narrow chest

Platyspondyly

Skeletal dysplasia

Disease(s) Associated with NEK1

asphyxiating thoracic dystrophy

short-rib thoracic dysplasia 6 with or without polydactyly

Mouse Phenotypes		abnormal cranium morphology	domed cranium	short tibia	abnormal pelvic girdle bone morphology	abnormal bone structure	decreased bone mineral content
Availability	Mouse Genotype	abnormal cranium morphology	domed cranium	short tibia	abnormal pelvic girdle bone morphology	abnormal bone structure	decreased bone mineral content
	Nek1^em1(IMPC)Bay/Nek1^em1(IMPC)Bay
	Nek1^kat/Nek1^kat

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23