|
Symbol Name ID |
Myc
myelocytomatosis oncogene MGI:97250 |
| Darker colors indicate more annotations |
| Human Phenotypes | Gangrene |
| Disease(s) Associated with MYC | |
| acute promyelocytic leukemia |
| Mouse Phenotypes | abnormal intestinal goblet cell morphology |
abnormal intracellular organelle morphology |
abnormal cell nucleus morphology |
binucleate |
abnormal chromosome number |
aneuploidy |
polyploidy |
abnormal hepatocyte mitochondrial morphology |
abnormal cell cycle |
abnormal mitosis |
increased B cell apoptosis |
increased male germ cell apoptosis |
focal hepatic necrosis |
decreased B cell proliferation |
increased B cell proliferation |
decreased T cell proliferation |
abnormal enterocyte proliferation |
decreased fibroblast proliferation |
absent fibroblast proliferation |
decreased cell proliferation |
chromosomal instability |
induced chromosome breakage |
spontaneous chromosome breakage |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Bmyctm1Mpo/Bmyctm1Mpo | ||||||||||||||||||||||||
| Myctm1.1Itl/Myctm1.1Itl | ||||||||||||||||||||||||
| Myctm1Atp/Myctm1Atp | ||||||||||||||||||||||||
| Myctm1Jlc/Myctm1Jlc | ||||||||||||||||||||||||
| Myctm1Lbox/Myctm1Lbox | ||||||||||||||||||||||||
| Myctm4.1Fwa/Myctm4.1Fwa | ||||||||||||||||||||||||
| Tg(HBVX*,-Myc)#Skp/Tg(HBVX*,-Myc)#Skp | ||||||||||||||||||||||||
| Myctm1Atp/Myc+ | ||||||||||||||||||||||||
| Myctm1Atp/Myctm2.1Atp | ||||||||||||||||||||||||
| Myctm2.1Atp/Myc+ | ||||||||||||||||||||||||
| Myctm37Mnz/Myc+ | ||||||||||||||||||||||||
| Myctm39Mnz/Myc+ | ||||||||||||||||||||||||
| Tg(IghMyc)22Bri/0 | ||||||||||||||||||||||||
| Tg(IghMyc)186Brn/0 | ||||||||||||||||||||||||
| Gt(ROSA)26Sortm1(Myc)Rcse/Gt(ROSA)26Sortm1(Myc)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Gt(ROSA)26Sortm2(myc*T58A)Rcse/Gt(ROSA)26Sortm2(myc*T58A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Gt(ROSA)26Sortm3(myc*S62A)Rcse/Gt(ROSA)26Sortm3(myc*S62A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Myctm2.1Atp/Myctm2.1Atp Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Myctm2Fwa/Myctm2Fwa Cd19tm1(cre)Cgn/Cd19+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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