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Symbol
Name
ID
Tlr4
toll-like receptor 4
MGI:96824
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Joint stiffness
Low back pain
Osteoporosis
Arthritis
Gout
Osteoarthritis
Polyarticular arthritis
Disease(s) Associated with TLR4
Behcet's disease
coronary artery disease
familial mediterranean fever
temporal arteritis

Mouse Phenotypes
abnormal osteoclast differentiation
decreased susceptibility to induced arthritis
increased susceptibility to induced arthritis
abnormal bone structure
increased bone mineral content
increased bone mineral density
increased bone mass
decreased susceptibility to bone fracture
Availability Mouse Genotype
Tlr4Lps-d/Tlr4Lps-d
Tlr4lps-del/Tlr4lps-del
Tlr4tm1Aki/Tlr4tm1Aki

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory