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Symbol Name ID |
Kras
Kirsten rat sarcoma viral oncogene homolog MGI:96680 |
| * | Aspects of the system are reported to show a normal phenotype. |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Death in early adulthood |
Death in infancy |
| Disease(s) Associated with KRAS | ||
| Lynch syndrome |
| Mouse Phenotypes | mortality/aging |
decreased survivor rate |
premature death |
lethality throughout fetal growth and development, complete penetrance |
perinatal lethality, complete penetrance |
perinatal lethality, incomplete penetrance |
postnatal lethality, complete penetrance |
postnatal lethality, incomplete penetrance |
embryonic lethality during organogenesis, complete penetrance |
embryonic lethality during organogenesis, incomplete penetrance |
embryonic lethality, complete penetrance |
prenatal lethality, complete penetrance |
prenatal lethality, incomplete penetrance |
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| Availability | Mouse Genotype | |||||||||||||
| Krastm1Bbd/Krastm1Bbd | ||||||||||||||
| Krastm1Mok/Krastm1Mok | ||||||||||||||
| Krastm1Tyj/Krastm1Tyj | ! | |||||||||||||
| Krastm3Bbd/Krastm3Bbd | ||||||||||||||
| Krastm3Tyj/Krastm3Tyj | ||||||||||||||
| Krastm4.1Bbd/Krastm4.1Bbd | ! | ! | ||||||||||||
| Krastm2Tyj/Kras+ | ! | |||||||||||||
| Krastm3Tyj/Kras+ | ! | |||||||||||||
| Krastm4.1Bbd/Kras+ | ||||||||||||||
| Krastm4.1Tyj/Kras+ | ||||||||||||||
| Krastm1Bbd/Krastm2Bbd Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd (conditional) |
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| Krastm1Bbd/Kras+ Polr2atm1(cre/ERT2)Bbd/Polr2atm1(cre/ERT2)Bbd (conditional) |
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| Krastm1.1Khai/Kras+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Krastm1Bbd/Kras+ Tg(CMV-cre)1Cgn/? (conditional) |
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| Krastm1Bbd/Kras+ Tg(CMV-cre/ERT)1Ipc/0 (conditional) |
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| Krastm1Bbd/Kras+ (conditional) | ||||||||||||||
| Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Krastm4Tyj/Kras+ Tg(Scgb1a1-cre)1Kkw/? (conditional) |
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| Krastm4Tyj/Kras+ Tg(Prm-cre)58Og/0 (conditional) |
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| Krastm4Tyj/Kras+ Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Krastm4Tyj/Kras+ Meox2tm1(cre)Sor/Meox2+ (conditional) |
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| Krastm4Tyj/Kras+ Tg(Fabp7-cre,-lacZ)3Gtm/0 (conditional) |
* | |||||||||||||
| Krastm4Tyj/Kras+ (conditional) | ||||||||||||||
| Krastm4Tyj/Kras+ Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Krastm4Tyj/Kras+ Scgb1a1tm1.1(cre)Fjd/Scgb1a1+ (conditional) |
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| Krastm4Tyj/Kras+ Tg(Cdh5-cre/ERT2)1Rha/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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