|
Symbol Name ID |
Kras
Kirsten rat sarcoma viral oncogene homolog MGI:96680 |
| Darker colors indicate more annotations |
| Human Phenotypes | Low posterior hairline |
Frontal bossing |
Prominent occiput |
Parietal bossing |
Biparietal narrowing |
Cranial asymmetry |
Left unilambdoid synostosis |
Sagittal craniosynostosis |
Dolichocephaly |
Scaphocephaly |
Plagiocephaly |
Micrognathia |
Giant cell granuloma of mandible |
Hypoplasia of the zygomatic bone |
Dandy-Walker malformation |
Macrocephaly |
Abnormal facial shape |
Coarse facial features |
Facial asymmetry |
Long face |
Triangular face |
Preauricular skin tag |
Full cheeks |
Midface retrusion |
Adenoma sebaceum |
Broad forehead |
High forehead |
Thick lower lip vermilion |
Long philtrum |
Submucous cleft hard palate |
High palate |
Salivary gland neoplasm |
Abnormal dental morphology |
Abnormality of dental color |
Anteverted nares |
Depressed nasal bridge |
Hypoplastic nasal bridge |
Wide nasal bridge |
Short nose |
Abnormal conjunctiva morphology |
Limbal dermoid |
Aplasia/Hypoplasia of the eyebrow |
Absent eyebrow |
Abnormal eyelash morphology |
Sparse or absent eyelashes |
Blepharophimosis |
Long palpebral fissure |
Short palpebral fissure |
Downslanted palpebral fissures |
Eyelid coloboma |
Epicanthus |
Telecanthus |
Underdeveloped supraorbital ridges |
| Disease(s) Associated with KRAS | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| cardiofaciocutaneous syndrome | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| cardiofaciocutaneous syndrome 2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| linear nevus sebaceous syndrome | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lynch syndrome | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Noonan syndrome | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| Noonan syndrome 3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| oculoectodermal syndrome |
| Mouse Phenotypes | abnormal cranium morphology |
decreased cranium length |
increased cranium height |
increased cranium width |
abnormal facial morphology |
triangular face |
flattened snout |
increased facial tumor incidence |
increased lip tumor incidence |
abnormal ear position |
|
| Availability | Mouse Genotype | ||||||||||
| Krastm4.1Bbd/Krastm4.1Bbd | |||||||||||
| Krastm4Tyj/Kras+ Krt19tm1(cre/ERT)Ggu/Krt19+ (conditional) |
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| Krastm4Tyj/Kras+ Tg(Krt1-15-cre/PGR*)22Cot/0 (conditional) |
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| Krastm4Tyj/Kras+ Tg(IVL-cre/ERT2)1Blpn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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