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Symbol
Name
ID

Itgb2
integrin beta 2
MGI:96611

Phenotype annotations related to integument

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Perianal abscess	Recurrent skin infections	Chronic mucocutaneous candidiasis	Chronic oral candidiasis	Nail dystrophy	Poor wound healing	Skin ulcer	Pyoderma gangrenosum
Disease(s) Associated with ITGB2	Perianal abscess	Recurrent skin infections	Chronic mucocutaneous candidiasis	Chronic oral candidiasis	Nail dystrophy	Poor wound healing	Skin ulcer	Pyoderma gangrenosum
leukocyte adhesion deficiency
leukocyte adhesion deficiency 1

Mouse Phenotypes

integument phenotype

dermatitis

alopecia

abnormal hair follicle dermal papilla morphology

abnormal dermal layer morphology

mixed cellular infiltration to dermis

abnormal epidermal layer morphology

hyperkeratosis

orthokeratosis

parakeratosis

acanthosis

epidermal hyperplasia

reddish skin

scaly skin

spontaneous skin ulceration

abnormal skin condition

psoriasis

Availability

Mouse Genotype

Itgb2^tm1Bay/Itgb2^tm1Bay

*!

!

!

Itgb2^tm2Bay/Itgb2^tm2Bay

*

Itgb2^tm1Bay/Itgb2^tm2Bay

*!

!

!

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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