About   Help   FAQ
Symbol
Name
ID 		Icam1
intercellular adhesion molecule 1
MGI:96392
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA concentration
Increased circulating IgG concentration
Decreased circulating immunoglobulin concentration
Paraproteinemia
Lymphadenopathy
Splenomegaly
Iridocyclitis
Epididymitis
Erythema nodosum
Autoimmunity
Disease(s) Associated with ICAM1
Behcet's disease
biliary atresia
multiple myeloma
type 1 diabetes mellitus

Mouse Phenotypes
immune system phenotype
abnormal leukocyte migration
abnormal cellular extravasation
abnormal leukocyte tethering or rolling
abnormal leukocyte adhesion
decreased susceptibility to induced colitis
large intestinal inflammation
increased eosinophil cell number
increased neutrophil cell number
increased lymphocyte cell number
increased monocyte cell number
increased leukocyte cell number
abnormal macrophage morphology
impaired neutrophil recruitment
abnormal T cell physiology
abnormal interleukin level
abnormal tumor necrosis factor level
abnormal immune system physiology
decreased susceptibility to type IV hypersensitivity reaction
decreased susceptibility to endotoxin shock
decreased susceptibility to bacterial infection induced morbidity/mortality
decreased susceptibility to parasitic infection induced morbidity/mortality
Availability Mouse Genotype
Icam1tm1Alb/Icam1tm1Alb
Icam1tm1Bay/Icam1tm1Bay *
Icam1tm1Cws/Icam1tm1Cws
Icam1tm1Jcgr/Icam1tm1Jcgr *
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory