|
Symbol Name ID |
Hmox1
heme oxygenase 1 MGI:96163 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Insulin resistance |
Joint swelling |
| Disease(s) Associated with HMOX1 | |||||||||
| coronary artery disease | |||||||||
| factor VIII deficiency | |||||||||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal response to cardiac infarction |
increased myocardial infarct size |
increased blood urea nitrogen level |
decreased circulating free fatty acids level |
decreased circulating iron level |
increased circulating tumor necrosis factor level |
decreased circulating alanine transaminase level |
increased circulating alanine transaminase level |
decreased circulating aspartate transaminase level |
increased circulating ferritin level |
abnormal thrombosis |
increased energy expenditure |
edema |
cerebral edema |
improved glucose tolerance |
increased insulin sensitivity |
abnormal iron homeostasis |
abnormal metabolism |
|
| Availability | Mouse Genotype | |||||||||||||||||||
| Hmox1tm1Mlee/Hmox1tm1Mlee | ||||||||||||||||||||
| Hmox1tm1Poss/Hmox1tm1Poss | ||||||||||||||||||||
| Hmox1em1(IMPC)Mbp/Hmox1+ | ||||||||||||||||||||
| Hmox1tm1Ysh/Hmox1+ | ||||||||||||||||||||
| Hmox1tm1.1Gkl/Hmox1tm1.1Gkl Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Hmox1tm1.1Hes/Hmox1tm1.1Hes Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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| Hmox1tm1.1Hes/Hmox1tm1.1Hes Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Hmox1tm1.1Hes/Hmox1tm1.1Hes Tg(Ckmm-cre)5Khn/0 (conditional) |
* | |||||||||||||||||||
| Hmox1tm1.1Hes/Hmox1tm1.1Hes Tg(Fabp4-cre)1Rev/0 (conditional) |
* | |||||||||||||||||||
| Hmox1tm1.1Hes/Hmox1tm1.1Hes Tg(Ins2-cre)25Mgn/0 (conditional) |
* | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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