Symbol
Name
ID

Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
MGI:95820

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Depression	Negativism	Personality changes	Addictive alcohol use
Disease(s) Associated with GRIN2A	Depression	Negativism	Personality changes	Addictive alcohol use
alcohol dependence
Huntington's disease
schizophrenia

Mouse Phenotypes

behavior/neurological phenotype

impaired contextual conditioning behavior

decreased exploration in new environment

abnormal spatial learning

abnormal spatial working memory

abnormal depression-related behavior

decreased anxiety-related response

increased startle reflex

impaired coordination

jumpy

decreased vertical activity

decreased chemical nociceptive threshold

decreased chemically-elicited antinociception

allodynia

decreased thermal nociceptive threshold

decreased kindling response

Availability

Mouse Genotype

Grin2a^tm1.1Jpleo/Grin2a^tm1.1Jpleo

Grin2a^tm1.1Ppao/Grin2a^tm1.1Ppao

Grin2a^tm1.1Tnkw/Grin2a^tm1.1Tnkw

Grin2a^tm1Mim/Grin2a^tm1Mim

Grin2a^tm1Nak/Grin2a^tm1Nak

Grin2a^tm1Rsp/Grin2a^tm1Rsp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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