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Symbol
Name
ID
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
MGI:95758
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Type II diabetes mellitus
Insulin resistance
Disease(s) Associated with SLC2A4
type 2 diabetes mellitus

Mouse Phenotypes
homeostasis/metabolism phenotype
increased cardiac muscle glycogen level
abnormal response to cardiac infarction
increased insulin secretion
abnormal circulating glucose level
increased circulating glucose level
hyperglycemia
increased circulating insulin level
decreased circulating ketone body level
decreased circulating free fatty acids level
abnormal glucose homeostasis
abnormal glucose tolerance
impaired glucose tolerance
abnormal glycogen homeostasis
increased liver glycogen level
decreased skeletal muscle glycogen level
insulin resistance
abnormal lipid homeostasis
abnormal lipid level
decreased fatty acids level
decreased triglyceride level
Availability Mouse Genotype
Slc2a4tm1Jdz/Slc2a4tm1Jdz
Slc2a4tm1Mch/Slc2a4tm1Mch *
Slc2a4tm1Mch/Slc2a4+ *
Slc2a4tm1Abel/Slc2a4tm1Abel
Tg(Myhca-cre)1Abel/?  (conditional)
Slc2a4tm1Abel/Slc2a4tm1Abel
Tg(Fabp4-cre)1Abel/?  (conditional)
Slc2a4tm1Abel/Slc2a4tm1Abel
Tg(Ckmm-cre)5Khn/?  (conditional)
Slc2a4tm1Abel/Slc2a4tm1Abel
Tg(Ckmm-cre)5Khn/0  (conditional)
Slc2a4tm1Jdz/Slc2a4tm1Jdz
Tg(ACTA1-cre)1Jdz/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory