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Symbol
Name
ID

Gja1
gap junction protein, alpha 1
MGI:95713

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Abnormality of chromosome segregation	Hypoglycemia	Diabetes mellitus	Cerebral calcification	Basal ganglia calcification
Disease(s) Associated with GJA1	Abnormality of chromosome segregation	Hypoglycemia	Diabetes mellitus	Cerebral calcification	Basal ganglia calcification
erythrokeratodermia variabilis
hypoplastic left heart syndrome
oculodentodigital dysplasia

Mouse Phenotypes		abnormal vascular wound healing	abnormal blood homeostasis	abnormal circulating hormone level	cyanosis	edema	lymphedema	impaired skin barrier function
Availability	Mouse Genotype	abnormal vascular wound healing	abnormal blood homeostasis	abnormal circulating hormone level	cyanosis	edema	lymphedema	impaired skin barrier function
	Gja1^{em1(IMPC)Ccpcz}/Gja1^{em1(IMPC)Ccpcz}
	Gja1^tm1Kdr/Gja1^tm1Kdr
	Gja1^tm3.1Clo/Gja1^tm3.1Clo
	Gja1^tm4Kwi/Gja1^tm4Kwi
	Gja1^tm1Dlg/Gja1^tm1Dlg Tg(Tek-cre)1Ywa/0 (conditional)
	Gja1^tm1Kwi/Gja1⁺ Tg(KRT5-cre)5132Jlj/0 (conditional)
	Gja1^tm1Kwi/Gja1^{tm5(cre/ERT)Kwi} (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 06/16/2026 MGI 6.24