Symbol Name ID |
Fgfr2
fibroblast growth factor receptor 2 MGI:95523 |
Darker colors indicate more annotations |
Human Phenotypes | Ulnar bowing |
Femoral bowing |
Genu valgum |
Partial duplication of the distal phalanx of the 2nd finger |
Partial duplication of the distal phalanx of the 3rd finger |
Radial deviation of the 3rd finger |
Clinodactyly of the 5th finger |
Postaxial hand polydactyly |
Shortening of all distal phalanges of the fingers |
Broad distal phalanx of the thumb |
Cone-shaped epiphyses of the phalanges of the hand |
Absent proximal phalanx of thumb |
Shortening of all middle phalanges of the fingers |
Broad thumb |
Partial duplication of thumb phalanx |
Preaxial hand polydactyly |
Symphalangism affecting the phalanges of the hand |
Triphalangeal thumb |
Bilateral triphalangeal thumbs |
Short thumb |
Arachnodactyly |
Broad proximal phalanx of the hallux |
Broad distal phalanx of the hallux |
Duplication of the distal phalanx of the hallux |
Broad hallux phalanx |
Broad hallux |
Broad distal hallux |
Hallux valgus |
Hallux varus |
Preaxial foot polydactyly |
Cone-shaped epiphyses of the toes |
Short middle phalanx of toe |
Overlapping toe |
Toe syndactyly |
2-3 toe syndactyly |
Preaxial polydactyly |
Brachydactyly |
Syndactyly |
Cutaneous syndactyly |
Cutaneous finger syndactyly |
Finger syndactyly |
2-3 finger syndactyly |
Abnormal fibula morphology |
Absent first metatarsal |
Broad first metatarsal |
Short first metatarsal |
Short metatarsal |
Broad metatarsal |
Metatarsus adductus |
Rocker bottom foot |
Calcaneonavicular fusion |
Metaphyseal widening |
Dislocated radial head |
Absent radius |
Hypoplasia of the radius |
Humeroradial synostosis |
Radioulnar synostosis |
Proximal radio-ulnar synostosis |
Hypoplasia of the ulna |
Split foot |
Palmoplantar cutis laxa |
Pes planus |
Talipes equinovarus |
Genu recurvatum |
Small thenar eminence |
Carpal bone malsegmentation |
Synostosis of carpal bones |
Single transverse palmar crease |
Bilateral single transverse palmar creases |
Joint contracture of the hand |
Elbow ankylosis |
Limited elbow movement |
Limited elbow extension |
Rhizomelic arm shortening |
Disease(s) Associated with FGFR2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
acrocephalosyndactylia | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Antley-Bixler syndrome without disordered steroidogenesis | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Beare-Stevenson cutis gyrata syndrome | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
craniosynostosis | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Jackson-Weiss syndrome | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lacrimoauriculodentodigital syndrome 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pfeiffer syndrome | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Saethre-Chotzen syndrome |
Mouse Phenotypes | abnormal apical ectodermal ridge morphology |
absent apical ectodermal ridge |
absent limb buds |
syndactyly |
short humerus |
short radius |
absent forelimb |
short femur |
short tibia |
absent hindlimb |
abnormal limb development |
absent limbs |
caudal vertebral fusion |
curly tail |
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Availability | Mouse Genotype | ||||||||||||||
Fgfr2hob/Fgfr2hob | |||||||||||||||
Fgfr2m1Sgg/Fgfr2m1Sgg | |||||||||||||||
Fgfr2tm1.1Dor/Fgfr2tm1.1Dor | |||||||||||||||
Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn | |||||||||||||||
Fgfr2tm1Cxd/Fgfr2tm1Cxd | |||||||||||||||
Fgfr2tm2.1Lni/Fgfr2tm2.1Lni | |||||||||||||||
Fgfr2tm3Dsn/Fgfr2tm3Dsn | |||||||||||||||
Fgfr2tm3Lni/Fgfr2tm3Lni | |||||||||||||||
Fgfr2tm1.1Dor/Fgfr2hob | |||||||||||||||
Fgfr2tm3.1Cxd/Fgfr2+ | |||||||||||||||
Fgfr2tm1Dor/Fgfr2tm1.1Dor Twist2tm1(cre)Dor/Twist2+ (conditional) |
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Fgfr2tm2Ewj/Fgfr2+ Tg(EIIa-cre)C5379Lmgd/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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