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Symbol
Name
ID

Fbn1
fibrillin 1
MGI:95489

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Abnormality of chromosome stability	Chromosome breakage	Abnormal circulating lipid concentration	Type II diabetes mellitus	Mitral annular calcification
Disease(s) Associated with FBN1	Abnormality of chromosome stability	Chromosome breakage	Abnormal circulating lipid concentration	Type II diabetes mellitus	Mitral annular calcification
Marfan syndrome
stiff skin syndrome
systemic scleroderma

Mouse Phenotypes		hemopericardium	decreased susceptibility to diet-induced obesity	decreased circulating leptin level	abnormal arterial thrombosis	decreased energy expenditure
Availability	Mouse Genotype	hemopericardium	decreased susceptibility to diet-induced obesity	decreased circulating leptin level	abnormal arterial thrombosis	decreased energy expenditure
	Fbn1^tm1Rmz/Fbn1^tm1Rmz
	Fbn1^tm2Rmz/Fbn1^tm2Rmz
	Fbn1^tm3Rmz/Fbn1^tm3Rmz
	Fbn1^em1Chop/Fbn1⁺
	Fbn1^tm1.1Itl/Fbn1^tm3Rmz Tg(CMV-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23