Symbol
Name
ID

Edn1
endothelin 1
MGI:95283

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Increased LDL cholesterol concentration

Hypercholesterolemia

Hypertriglyceridemia

Elevated circulating C-reactive protein concentration

Elevated erythrocyte sedimentation rate

Decreased resting energy expenditure

Glucose intolerance

Diabetes mellitus

Type II diabetes mellitus

Impaired glucose tolerance

Joint swelling

Fever

Disease(s) Associated with EDN1

coronary artery disease

obesity

rheumatoid arthritis

Mouse Phenotypes		decreased response of heart to induced stress	abnormal blood gas level	decreased circulating antidiuretic hormone level	decreased circulating sodium level	hypercapnia	hypoxia	decreased urine sodium level	abnormal urine homeostasis	increased urine osmolality
Availability	Mouse Genotype	decreased response of heart to induced stress	abnormal blood gas level	decreased circulating antidiuretic hormone level	decreased circulating sodium level	hypercapnia	hypoxia	decreased urine sodium level	abnormal urine homeostasis	increased urine osmolality
	Edn1^tm1Utj/Edn1⁺
	Edn1^tm1Ywa/Edn1^tm1Ywa Tg(Myh6-cre)2182Mds/0 (conditional)
	Edn1^tm1Ywa/Edn1^tm1Ywa Tg(AQP2-cre)2Dek/0 (conditional)
	Edn1^tm1Ywa/Edn1^tm1Ywa Tg(Aqp2-cre)1Dek/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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