|
Symbol Name ID |
Chm
CHM Rab escort protein MGI:892979 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Attenuation of retinal blood vessels |
Posterior subcapsular cataract |
Chorioretinal atrophy |
Chorioretinal scalloped atrophy |
Choroidal neovascularization |
Fundus hypopigmentation |
Granular macular appearance |
Macular edema |
Abnormal retinal pigmentation |
Nummular pigmentation of the retina |
Pigmentary retinopathy |
Spicular pigmentation of the retina |
Retinal pigment epithelial mottling |
Abnormal fundus autofluorescence imaging |
Abnormal electroretinogram |
Myopia |
Color vision defect |
Nyctalopia |
Visual impairment |
Constriction of peripheral visual field |
Peripheral visual field loss |
Progressive visual loss |
| Disease(s) Associated with CHM | ||||||||||||||||||||||
| choroideremia |
| Mouse Phenotypes | vision/eye phenotype |
abnormal retina vasculature morphology |
increased retina apoptosis |
abnormal Muller cell physiology |
decreased retina ganglion cell number |
decreased retina photoreceptor cell number |
abnormal retina bipolar cell morphology |
abnormal retina rod bipolar cell morphology |
abnormal retina horizontal cell morphology |
abnormal photoreceptor outer segment morphology |
short photoreceptor outer segment |
disorganized photoreceptor outer segment |
abnormal retina cone cell morphology |
retina cone cell degeneration |
abnormal retina rod cell morphology |
retina photoreceptor degeneration |
abnormal retina pigment epithelium morphology |
abnormal retina pigmentation |
abnormal ocular fundus morphology |
abnormal retina morphology |
thin retina outer nuclear layer |
decreased total retina thickness |
retina degeneration |
abnormal electroretinogram waveform feature |
decreased a-wave amplitude |
decreased b-wave amplitude |
abnormal rod electrophysiology |
abnormal vision |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Chmtm1.2Seab/Chm+ | |||||||||||||||||||||||||||||
| Chmtm1.3Seab/Chm+ | |||||||||||||||||||||||||||||
| Chmtm1Jvdh/Chm+ | * | ||||||||||||||||||||||||||||
| Chmtm1.1Seab/Chmtm1.1Seab Tg(Six3-cre)69Frty/0 (conditional) |
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| Chmtm1.1Seab/Y Tg(Six3-cre)69Frty/0 (conditional) |
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| Chmtm1Ynshn/Y Tg(Six3-cre)69Frty/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/16/2026 MGI 6.24 |
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