|
Symbol Name ID |
Cntf
ciliary neurotrophic factor MGI:88439 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Gliosis |
Cerebellar atrophy |
Neuronal loss in central nervous system |
Gait ataxia |
Bradykinesia |
Chorea |
Depression |
Personality changes |
Dementia |
Hyperreflexia |
Seizure |
| Disease(s) Associated with CNTF | |||||||||||
| Huntington's disease |
| Mouse Phenotypes | nervous system phenotype |
astrocytosis |
abnormal microglial cell morphology |
decreased oligodendrocyte progenitor number |
abnormal oligodendrocyte apoptosis |
abnormal axon extension |
abnormal neuron proliferation |
abnormal astrocyte physiology |
increased cerebral infarct size |
abnormal motor neuron morphology |
decreased motor neuron number |
motor neuron degeneration |
abnormal myelin sheath morphology |
decreased neuronal precursor cell number |
axon degeneration |
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| Availability | Mouse Genotype | |||||||||||||||
| Cntftm1Gdy/Cntftm1Gdy | * | |||||||||||||||
| Cntftm1Mpin/Cntftm1Mpin | * | |||||||||||||||
| Cntftm1Vlcg/Cntftm1Vlcg | * | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/16/2026 MGI 6.24 |
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