Symbol
Name
ID

Ctnnb1
catenin beta 1
MGI:88276

Phenotype annotations related to limbs/digits/tail

Darker colors indicate more annotations

Human Phenotypes	Broad finger
Disease(s) Associated with CTNNB1	Broad finger
autosomal dominant intellectual developmental disorder 19

Mouse Phenotypes

abnormal apical ectodermal ridge morphology

abnormal autopod morphology

polydactyly

abnormal forelimb morphology

abnormal humerus morphology

absent deltoid tuberosity

decreased diameter of humerus

absent radius

abnormal ulna morphology

short ulna

abnormal hindlimb morphology

absent hindlimb

abnormal limb development

ectopic limbs

short limbs

Availability

Mouse Genotype

Ctnnb1^tm1Mmt/Ctnnb1^tm1Mmt
Tg(Msx2-cre)5Rem/0 (conditional)

Ctnnb1^tm1Yy/Ctnnb1^tm1Yy
Tg(Col2a1-cre)1Bhr/0 (conditional)

Ctnnb1^tm1Yy/Ctnnb1^tm1Yy
Tg(Prnp-GFP/cre)1Blw/0 (conditional)

Ctnnb1^tm1Yy/Ctnnb1^tm1Yy
Tg(Prrx1-cre)1Cjt/0 (conditional)

Ctnnb1^tm2Kem/Ctnnb1^tm2Kem
Tg(Col2a1-cre)1Bhr/0 (conditional)

Ctnnb1^tm2Kem/Ctnnb1^tm2Kem
Tg(Msx2-cre)5Rem/0 (conditional)

Ctnnb1^tm4Wbm/Ctnnb1^tm4Wbm
Tg(Prrx1-cre)98Mlgn/0 (conditional)

Ctnnb1^tm1Max/Ctnnb1^tm2Kem
Tg(Msx2-cre)5Rem/0 (conditional)

Ctnnb1^tm1Max/Ctnnb1^tm2Kem
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional)

Ctnnb1^tm1Mmt/Ctnnb1⁺
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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