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Symbol
Name
ID
C3
complement component 3
MGI:88227
Phenotype annotations related to vision/eye
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Macular degeneration
Retinopathy
Disease(s) Associated with C3
age related macular degeneration 7
sickle cell anemia
systemic lupus erythematosus

Mouse Phenotypes
vision/eye phenotype
abnormal retina rod bipolar cell morphology
abnormal retina horizontal cell morphology
decreased b-wave amplitude
abnormal c-wave shape
abnormal eye electrophysiology
Availability Mouse Genotype
C3tm1Crr/C3tm1Crr *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory