Symbol Name ID |
Bmp4
bone morphogenetic protein 4 MGI:88180 |
Darker colors indicate more annotations |
Human Phenotypes | Sparse scalp hair |
Brachycephaly |
Lambdoidal craniosynostosis |
Plagiocephaly |
Micrognathia |
Retrognathia |
Aplasia of the maxilla |
Small sella turcica |
Microcephaly |
Facial asymmetry |
Short face |
Midface retrusion |
High forehead |
Cleft lip |
Eclabion |
Bifid uvula |
Cleft palate |
High palate |
Microglossia |
Abnormal dental morphology |
Short dental root |
Taurodontia |
Peg-shaped maxillary lateral incisors |
Abnormal primary molar morphology |
Microdontia |
Agenesis of central incisor |
Agenesis of lateral incisor |
Agenesis of maxillary lateral incisor |
Agenesis of permanent teeth |
Tooth agenesis |
Anodontia |
Hypodontia |
Oligodontia |
Oligodontia of primary teeth |
Selective tooth agenesis |
Agenesis of molar |
Agenesis of permanent molar |
Agenesis of first permanent molar tooth |
Agenesis of premolar |
Agenesis of mandibular premolar |
Abnormality of canine |
Delayed eruption of teeth |
Delayed eruption of permanent teeth |
Enamel hypoplasia |
Hypoplasia of teeth |
Abnormality of primary teeth |
Dental malocclusion |
Widely spaced teeth |
Orofacial cleft |
Impaired mastication |
Sparse eyebrow |
Short eyelashes |
Orbital cyst |
Disease(s) Associated with BMP4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
orofacial cleft 11 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
syndromic microphthalmia 6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
tooth agenesis |
Mouse Phenotypes | abnormal pharyngeal arch artery morphology |
large anterior fontanelle |
short frontal bone |
small interparietal bone |
abnormal mandible morphology |
retrognathia |
short nasal bone |
abnormal face development |
abnormal snout morphology |
|
Availability | Mouse Genotype | |||||||||
Bmp4tm1Blh/Bmp4+ | ||||||||||
Bmp4tm1Jfm/Bmp4tm1Jfm H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
||||||||||
Bmp4tm3Blh/Bmp4tm3Blh Foxg1tm1(cre)Skm/Foxg1+ (conditional) |
||||||||||
Bmp4tm1Jfm/Bmp4tm1.1Jfm Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 03/19/2024 MGI 6.23 |
|
|