Symbol
Name
ID

B2m
beta-2 microglobulin
MGI:88127

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Abnormal circulating IgA level

Decreased circulating IgG level

Abnormal circulating IgM level

Decreased specific antibody response to polysaccharide vaccine

Decreased HDL cholesterol concentration

Elevated circulating creatinine concentration

Hypoalbuminemia

Decreased circulating apolipoprotein A-I concentration

Decreased circulating beta-2-microglobulin level

Hypoproteinemia

Elevated erythrocyte sedimentation rate

Edema

Abnormal urinary electrolyte concentration

Hematuria

Proteinuria

Generalized amyloid deposition

Renal amyloidosis

Renal interstitial amyloid deposits

Disease(s) Associated with B2M

familial visceral amyloidosis

immunodeficiency 43

Mouse Phenotypes		increased circulating phosphate level	decreased circulating serum albumin level	abnormal glucose homeostasis	hemochromatosis	abnormal interleukin level	abnormal tumor necrosis factor level
Availability	Mouse Genotype	increased circulating phosphate level	decreased circulating serum albumin level	abnormal glucose homeostasis	hemochromatosis	abnormal interleukin level	abnormal tumor necrosis factor level
	B2m^tm1Jae/B2m^tm1Jae
	B2m^tm1Unc/B2m^tm1Unc
	B2m^{tm1b(EUCOMM)Wtsi}/B2m⁺
	B2m^tm1Jae/B2m^tm1Jae Tg(B2m)1Rms/0 Tg(INS-cre)2Rms/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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