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Symbol
Name
ID
Akt1
thymoma viral proto-oncogene 1
MGI:87986
Phenotype annotations related to growth/size/body
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hemihypertrophy
Splenomegaly
Hepatosplenomegaly
Peritoneal abscess
Weight loss
Disease(s) Associated with AKT1
chronic myeloid leukemia
pancreatic cancer
Proteus syndrome

Mouse Phenotypes
biliary cyst
growth/size/body region phenotype
decreased lean body mass
decreased body weight
decreased susceptibility to diet-induced obesity
decreased body size
postnatal growth retardation
decreased fetal size
Availability Mouse Genotype
Akt1tm1Hem/Akt1tm1Hem
Akt1tm1Mbb/Akt1tm1Mbb
Akt1tm1Nhy/Akt1tm1Nhy
Akt1tm2.1Mbb/Akt1tm2.1Mbb
Akt1tm1.1Mjl/Akt1+
Akt1tm2Mbb/Akt1tm2Mbb
Tg(Nes-cre)1Kln/0  (conditional)
*
Akt1tm2Mbb/Akt1tm2Mbb
Tg(Ckmm-cre)5Khn/0  (conditional)
*
Akt1tm1Mjl/Akt1+
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sortm1(cre/ERT)Nat  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory