Symbol
Name
ID

Chrnb2
cholinergic receptor nicotinic beta 2 subunit
MGI:87891

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Involuntary movements

Increased theta frequency activity in EEG

Interictal epileptiform activity

EEG with focal spikes

Depression

Attention deficit hyperactivity disorder

Suicidal ideation

Anxiety

Psychotic mentation

Atypical behavior

Motor stereotypy

Cognitive impairment

Mild intellectual disability

Sleep walking

NREM parasomnia

Paroxysmal dystonia

Seizure

Bilateral tonic-clonic seizure

Focal hyperkinetic seizure

Nocturnal seizures

Disease(s) Associated with CHRNB2

autosomal dominant nocturnal frontal lobe epilepsy

autosomal dominant nocturnal frontal lobe epilepsy 3

Mouse Phenotypes		seizures	increased susceptibility to induction of seizure by inducing agent	abnormal brain morphology	abnormal superior colliculus morphology	abnormal lateral geniculate nucleus morphology	abnormal nervous system electrophysiology	abnormal brain wave pattern	abnormal brain delta wave pattern	abnormal nicotine-mediated receptor currents
Availability	Mouse Genotype	seizures		abnormal brain morphology	abnormal superior colliculus morphology	abnormal lateral geniculate nucleus morphology	abnormal nervous system electrophysiology	abnormal brain wave pattern	abnormal brain delta wave pattern	abnormal nicotine-mediated receptor currents
	Chrnb2^tm1.1Cont/Chrnb2^tm1.1Cont
	Chrnb2^tm1Jpc/Chrnb2^tm1Jpc
	Chrnb2^tm1Mdb/Chrnb2^tm1Mdb
	Chrnb2^tm1.1Cont/Chrnb2⁺
	Tg(Prnp-tTA)F959Sbp/0 Tg(tetO-Chrnb2*V287L)H3Gica/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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