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Symbol
Name
ID
Zfp335
zinc finger protein 335
MGI:2682313
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Primary microcephaly
Spasticity
Gliosis
Delayed CNS myelination
Simplified gyral pattern
Agenesis of corpus callosum
Reduced cerebral white matter volume
Cerebral atrophy
Cerebellar hemisphere hypoplasia
Cerebellar atrophy
Severe global developmental delay
Disease(s) Associated with ZNF335
primary autosomal recessive microcephaly 10

Mouse Phenotypes
decreased brain size
loss of cortex neurons
thin cerebral cortex
Availability Mouse Genotype
Zfp335tm1.1Caw/Zfp335tm1.1Caw
Emx1tm1(cre)Krj/Emx1+  (conditional)
Zfp335tm1.1Caw/Zfp335+
Emx1tm1(cre)Krj/Emx1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory