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Symbol
Name
ID

Sik3
SIK family kinase 3
MGI:2446296

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Mouse Phenotypes

decreased susceptibility to diet-induced obesity

abnormal homeostasis

decreased blood urea nitrogen level

increased circulating bilirubin level

decreased circulating fructosamine level

decreased circulating glucose level

abnormal circulating hormone level

decreased circulating insulin level

decreased circulating leptin level

decreased circulating HDL cholesterol level

decreased circulating cholesterol level

decreased circulating triglyceride level

decreased circulating VLDL triglyceride level

increased circulating triglyceride level

decreased circulating calcium level

decreased circulating potassium level

increased circulating sodium level

abnormal circulating protein level

decreased circulating alanine transaminase level

increased circulating alanine transaminase level

increased circulating alkaline phosphatase level

increased circulating amylase level

increased core body temperature

abnormal energy homeostasis

increased oxygen consumption

increased respiratory quotient

abnormal glucose homeostasis

improved glucose tolerance

increased adiponectin level

abnormal lipid homeostasis

increased bile salt level

abnormal cholesterol level

decreased liver cholesterol level

increased liver cholesterol level

decreased liver triglyceride level

abnormal retinol level

Availability

Mouse Genotype

Sik3^{tm1a(EUCOMM)Hmgu}/Sik3^{tm1a(EUCOMM)Hmgu}

Sik3^tm1Htake/Sik3^tm1Htake

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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