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Symbol
Name
ID

Fscn2
fascin actin-bundling protein 2
MGI:2443337

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Human Phenotypes

Abnormal retinal vascular morphology

Attenuation of retinal blood vessels

Keratoconus

Posterior subcapsular cataract

Chorioretinal atrophy

Optic atrophy

Optic disc pallor

Abnormality of retinal pigmentation

Bone spicule pigmentation of the retina

Retinal degeneration

Rod-cone dystrophy

Abnormal electroretinogram

Nystagmus

Ophthalmoplegia

Nyctalopia

Progressive night blindness

Photophobia

Photopsia

Visual impairment

Blindness

Peripheral visual field loss

Glaucoma

Disease(s) Associated with FSCN2

retinitis pigmentosa

retinitis pigmentosa 30

Mouse Phenotypes

abnormal photoreceptor inner segment morphology

photoreceptor inner segment degeneration

abnormal photoreceptor outer segment morphology

abnormal photoreceptor outer segment size

short photoreceptor outer segment

photoreceptor outer segment degeneration

abnormal retina morphology

thin retina inner nuclear layer

thin retina outer nuclear layer

retina outer nuclear layer degeneration

increased susceptibility to age-related retinal degeneration

decreased total retina thickness

retina degeneration

decreased a-wave amplitude

decreased b-wave amplitude

abnormal eye electrophysiology

abnormal cone electrophysiology

abnormal rod electrophysiology

abnormal vision

Availability

Mouse Genotype

Fscn2^em1Fhan/Fscn2^em1Fhan

Fscn2^tm1Sykk/Fscn2^tm1Sykk

Fscn2^tm2Sykk/Fscn2^tm2Sykk

Fscn2^tm1Sykk/Fscn2⁺

Fscn2^tm2Sykk/Fscn2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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