Symbol Name ID |
Dusp4
dual specificity phosphatase 4 MGI:2442191 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
decreased B cell apoptosis |
increased T cell proliferation |
increased CD4-positive, alpha-beta T cell number |
increased IgG1 level |
decreased IgG2a level |
abnormal macrophage physiology |
decreased interferon-gamma secretion |
decreased interleukin-10 secretion |
increased interleukin-10 secretion |
increased interleukin-12 secretion |
increased interleukin-13 secretion |
increased interleukin-4 secretion |
increased interleukin-6 secretion |
increased tumor necrosis factor secretion |
increased susceptibility to parasitic infection |
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Availability | Mouse Genotype | ||||||||||||||||
Dusp4Gt(XG164)Byg/Dusp4Gt(XG164)Byg | * | ||||||||||||||||
Dusp4tm1Jmol/Dusp4tm1Jmol | |||||||||||||||||
Dusp4tm1Plev/Dusp4tm1Plev |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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