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Symbol Name ID |
Dicer1
dicer 1, ribonuclease type III MGI:2177178 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Colorectal polyposis |
Hereditary nonpolyposis colorectal carcinoma |
Neoplasm of the stomach |
Hepatocellular carcinoma |
Thyroid carcinoma |
Papillary thyroid carcinoma |
Sertoli cell neoplasm |
Testicular seminoma |
Ovarian neoplasm |
Uterine leiomyosarcoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Pilomatrixoma |
Basal cell carcinoma |
Rhabdomyosarcoma |
Alveolar rhabdomyosarcoma |
Medulloblastoma |
Cerebellar medulloblastoma |
Pleuropulmonary blastoma |
Medulloepithelioma |
| Disease(s) Associated with DICER1 | ||||||||||||||||||||
| colorectal cancer | ||||||||||||||||||||
| DICER1 syndrome | ||||||||||||||||||||
| hepatocellular carcinoma | ||||||||||||||||||||
| multinodular goiter |
| Mouse Phenotypes | neoplasm |
increased facial tumor incidence |
increased leukemia incidence |
increased myeloid sarcoma incidence |
increased hemolymphoid system tumor incidence |
|
| Availability | Mouse Genotype | |||||
| Dicer1tm1Mmk/Dicer1tm1Mmk Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional) |
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| Dicer1tm1Snj/Dicer1tm1Snj Tg(KRT5-cre/PGR)1Der/0 (conditional) |
* | |||||
| Dicer1tm1Tara/Dicer1tm1Tara Amhr2tm3(cre)Bhr/Amhr2+ (conditional) |
* | |||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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