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Symbol
Name
ID

Pcsk9
proprotein convertase subtilisin/kexin type 9
MGI:2140260

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Increased LDL cholesterol concentration
Disease(s) Associated with PCSK9	Increased LDL cholesterol concentration
familial hypercholesterolemia

Mouse Phenotypes		decreased circulating HDL cholesterol level	decreased circulating LDL cholesterol level	decreased circulating cholesterol level	increased circulating alkaline phosphatase level	increased circulating amylase level	increased circulating lipase level	increased bile salt level	abnormal cholesterol homeostasis
Availability	Mouse Genotype	decreased circulating HDL cholesterol level	decreased circulating LDL cholesterol level	decreased circulating cholesterol level	increased circulating alkaline phosphatase level	increased circulating amylase level	increased circulating lipase level	increased bile salt level	abnormal cholesterol homeostasis
	Pcsk9^m1Bms/Pcsk9^m1Bms
	Pcsk9^tm1.2Prat/Pcsk9^tm1.2Prat
	Pcsk9^tm1Jdh/Pcsk9^tm1Jdh
	Pcsk9^{tm2b(EUCOMM)Hmgu}/Pcsk9^{tm2b(EUCOMM)Hmgu}
	Pcsk9^m1Bms/Pcsk9⁺
	Pcsk9^tm1.1Prat/Pcsk9^tm1.1Prat Speer6-ps1^{Tg(Alb-cre)21Mgn}/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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