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Symbol
Name
ID
Twsg1
twisted gastrulation BMP signaling modulator 1
MGI:2137520
Phenotype annotations related to skeleton
Darker colors indicate more annotations

Mouse Phenotypes
thin neurocranium
abnormal jaw morphology
agnathia
short femur
abnormal limb bone morphology
abnormal caudal vertebrae morphology
decreased caudal vertebrae number
abnormal skeleton morphology
abnormal long bone epiphyseal plate morphology
abnormal long bone epiphyseal plate proliferative zone
decreased width of hypertrophic chondrocyte zone
abnormal thoracic vertebrae morphology
abnormal intervertebral disk morphology
abnormal intervertebral disk development
abnormal vertebrae morphology
abnormal cervical vertebrae morphology
decreased bone mineral density of lumbar vertebrae
abnormal vertebral arch development
abnormal vertebral arch morphology
abnormal vertebral lamina morphology
abnormal vertebral spinous process morphology
decreased bone mineral content
decreased bone mineral density of femur
decreased trabecular bone volume
decreased bone volume
decreased bone trabecula number
abnormal skeleton development
delayed endochondral bone ossification
abnormal intramembranous bone ossification
delayed bone ossification
Availability Mouse Genotype
Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
Twsg1tm1Ecan/Twsg1tm1Ecan
Twsg1tm1Emdr/Twsg1tm1Emdr
Twsg1tm1Nosa/Twsg1tm1Nosa

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory