Symbol
Name
ID

Sirt1
sirtuin 1
MGI:2135607

Phenotype annotations related to mortality/aging

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

mortality/aging

decreased survivor rate

premature death

lethality throughout fetal growth and development, incomplete penetrance

perinatal lethality

neonatal lethality, incomplete penetrance

perinatal lethality, incomplete penetrance

postnatal lethality

postnatal lethality, complete penetrance

postnatal lethality, incomplete penetrance

embryonic lethality during organogenesis, incomplete penetrance

preweaning lethality, incomplete penetrance

Availability

Mouse Genotype

Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd

Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu

Sirt1^{tm1b(EUCOMM)Wtsi}/Sirt1^{tm1b(EUCOMM)Wtsi}

Sirt1^tm1Fwa/Sirt1^tm1Fwa

Sirt1^tm1Mcby/Sirt1^tm1Mcby

Sirt1^tm2.1Fwa/Sirt1^tm2.1Fwa

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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