Symbol
Name
ID

Sirt1
sirtuin 1
MGI:2135607

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

heart right ventricle hypertrophy

abnormal tooth morphology

abnormal palatal rugae morphology

abnormal snout morphology

short snout

decreased embryo size

growth/size/body region phenotype

decreased body weight

slow postnatal weight gain

increased body weight

abnormal head morphology

decreased body length

decreased susceptibility to age related obesity

decreased body size

postnatal growth retardation

Availability

Mouse Genotype

Sirt1^tm1.1Cxd/Sirt1^tm1.1Cxd

Sirt1^tm1.1Ygu/Sirt1^tm1.1Ygu

Sirt1^{tm1b(EUCOMM)Wtsi}/Sirt1^{tm1b(EUCOMM)Wtsi}

Sirt1^tm1Fwa/Sirt1^tm1Fwa

Sirt1^tm1Mcby/Sirt1^tm1Mcby

Sirt1^tm2.1Fwa/Sirt1^tm2.1Fwa

Sirt1^tm3.1Mcby/Sirt1^tm3.1Mcby

Sirt1^tm3Fwa/Sirt1^tm3Fwa
Tg(Nes-cre)1Kln/0 (conditional)

Gt(ROSA)26Sor^{tm1(Sirt1)Ktm}/Gt(ROSA)26Sor⁺
Tg(Pomc1-cre)16Lowl/0 (conditional)

Gt(ROSA)26Sor^{tm1(Sirt1)Ktm}/Gt(ROSA)26Sor⁺
Tg(Agrp-cre)1Gsb/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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