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Symbol
Name
ID

Opa1
OPA1, mitochondrial dynamin like GTPase
MGI:1921393

Phenotype annotations related to hearing/vestibular/ear

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Sensorineural hearing impairment	Progressive sensorineural hearing impairment
Disease(s) Associated with OPA1	Sensorineural hearing impairment	Progressive sensorineural hearing impairment
dominant optic atrophy plus syndrome
mitochondrial DNA depletion syndrome 14
optic atrophy

Mouse Phenotypes		hearing/vestibular/ear phenotype	increased or absent threshold for auditory brainstem response	deafness
Availability	Mouse Genotype	hearing/vestibular/ear phenotype		deafness
	Opa1^M1Bewi/Opa1⁺	*
	Opa1^tm1.1Geno/Opa1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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