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Symbol
Name
ID

Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor 6
MGI:1920591

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

enhanced B cell migration

decreased B cell proliferation

decreased T cell proliferation

abnormal B cell number

decreased mature B cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased lymphocyte cell number

abnormal T cell physiology

enlarged lymph nodes

abnormal humoral immune response

decreased interleukin-2 secretion

Availability

Mouse Genotype

Arhgef6^tm1Kdf/Arhgef6^tm1Kdf

Arhgef6^{tm2e.1(EUCOMM)Wtsi}/Arhgef6^{tm2e.1(EUCOMM)Wtsi}

Arhgef6^{tm2e.1(EUCOMM)Wtsi}/Y

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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