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Symbol
Name
ID
Lrpprc
leucine-rich PPR-motif containing
MGI:1919666
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Decreased activity of mitochondrial respiratory chain
Decreased activity of mitochondrial complex I
Decreased activity of mitochondrial complex II
Decreased activity of mitochondrial complex III
Decreased activity of mitochondrial complex IV
Decreased activity of the pyruvate dehydrogenase complex
Disease(s) Associated with LRPPRC
French Canadian Leigh disease
Leigh disease

Mouse Phenotypes
increased mitochondrial DNA content
increased mitochondrial size
abnormal mitochondrial physiology
Availability Mouse Genotype
Lrpprctm1.1Lrsn/Lrpprctm1.1Lrsn
Tg(Ckmm-cre)5Khn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory