Symbol
Name
ID

Ift74
intraflagellar transport 74
MGI:1914944

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hypogonadism	Irregularly shaped sperm tail	Short sperm flagella	Reduced progressive sperm motility	Immotile sperm	Oligozoospermia	Male infertility
Disease(s) Associated with IFT74	Hypogonadism	Irregularly shaped sperm tail	Short sperm flagella	Reduced progressive sperm motility	Immotile sperm	Oligozoospermia	Male infertility
Bardet-Biedl syndrome 22
spermatogenic failure 58

Mouse Phenotypes

reproductive system phenotype

abnormal sperm axoneme morphology

absent sperm axonemal central pair

absent sperm flagellum

short sperm flagellum

oligozoospermia

teratozoospermia

abnormal sperm head morphology

abnormal spermatid morphology

spermiation failure

asthenozoospermia

immotile sperm

abnormal seminiferous tubule morphology

abnormal testis physiology

abnormal spermiogenesis

male infertility

Availability

Mouse Genotype

Ift74^{tm1b(EUCOMM)Hmgu}/Ift74^{tm1b(EUCOMM)Hmgu}

Ift74^{tm1c(EUCOMM)Hmgu}/Ift74^{tm1c(EUCOMM)Hmgu}
Tg(Stra8-icre)1Reb/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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