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Symbol
Name
ID
Dll4
delta like canonical Notch ligand 4
MGI:1859388
Phenotype annotations related to vision/eye
Darker colors indicate more annotations
Human Phenotypes
Cataract
Developmental cataract
Optic atrophy
Hypertelorism
Microphthalmia
Strabismus
Esotropia
Visual impairment
Disease(s) Associated with DLL4
Adams-Oliver syndrome

Mouse Phenotypes
abnormal retina vasculature morphology
abnormal induced retina neovascularization
Availability Mouse Genotype
Dll4tm1Nwg/Dll4+
Dll4tm2.1Vlcg/Dll4tm2.1Vlcg
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg/Gt(ROSA)26Sor+  (conditional)
Dll4tm2.1Vlcg/Dll4+
Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory